Hi.. Noob here. Regarding downsides to e-cigs, one I'm wondering concern I've thought about about seems valid to me-- prolonged storage of used moist cartomizers can develop mold undetected due to enclosure. Use of such a cartomizer could result in a major lung infection causing serious illness or death. I'd like to know if there is any data substantiating this concern, but to me, it sounds legit because you're drawing in foreign air particles (which can include airborne bacteria and viruse