I like Walt, have found that over time, the "throat hit" part vaping is no longer a part of what I am looking for. I started off with some 50/50 stuff at 18 mg of Nic. These days, I lean heavily towards the max VG stuff. Problem is, some Max VG's are like 70/30, which doesn't really cut it for me anymore. I want 80/20 or better from my Juice and I am down to 6 mg of nic. Hell, I use temp control these days because I don't like how hot the vapor gets on wattage mode. I don't need or more importantly, want a throat hit anymore. All I desire is a nicotine system that delivers my vice and brings some nice smooth flavor with it. The end goal is to be done with nicotine completely by the time I turn 40. That leaves me 21 months to work my way down even further on the Nic usage.
But definitely, the more Propylene Glycol and the higher your nicotine level, the harder it will be on your throat, regardless. Though personally, I don't find the first few vapes say after sleeping or a long session of being busy at work, to be any different than when I'm in the middle of a chain vape session. But I've been steadily refining my experience over the last 18 months or so. And I'm really glad I finally upgraded to a TC mod, it really is brilliant (to me at least).