The lower the resistance, (the fewer coils), the more vapor usually.
The higher the resistance, (the more coils), the more the flavor usually.
To achieve more flavor:
1. Use twisted wire. (I use 32, some vapers use 30). Twisted wire means you take a length of wire, fold it in half, tie the ends off, hook it onto a hook. Place the other loopy end onto a coat hanger, and twist that hanger around nice and consistantly in tension, until it's twisted nicely all the way down the line. Cut off a piece, and wrap your wick like normal. This doubles the wire, which doubles the juice, which doubles the flavor. A lot of peeps use the drill chuck on lowest speed, which works the best for perfect steady tension. (it twists in a second, so watch out lol!)
2. Use flat ribbon wire. (#6 is popular). The flat ribbon wire covers more wick area, which theoredically(sp) holds more juice. It's also great for having less hot spots for some reason. However, it is a bit trickier to set up.